Molecule Details
InChIKeyQKNBRNSGPNCARD-SGNKCFNYSA-N
Canonical SMILESCNc1ncc2cc(-c3ccc(-c4ncccc4F)cc3Cl)c(=O)n(C[C@H]3OC[C@H](N)CO3)c2n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Homologous
Avg pChEMBL6.92
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9Y2K2 SIK3 Homo sapiens Human PF00069 PF23312 7.9 IC50 ChEMBL
Q13177 PAK2 Homo sapiens Human PF00786 PF00069 7.4 IC50 ChEMBL
Q9H0K1 SIK2 Homo sapiens Human PF00069 PF23312 7.3 IC50 ChEMBL
P57059 SIK1 Homo sapiens Human PF00069 PF23312 7.3 IC50 ChEMBL
O75914 PAK3 Homo sapiens Human PF00786 PF00069 6.8 IC50 ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.7 IC50 ChEMBL
Q9UBE8 NLK Homo sapiens Human PF00069 6.6 IC50 ChEMBL
Q13153 PAK1 Homo sapiens Human PF00786 PF00069 6.2 IC50 ChEMBL
P45985 MAP2K4 Homo sapiens Human PF00069 6.1 IC50 ChEMBL