Molecule Details
| InChIKey | QKDBOJCTMDJVMH-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-[6-(4-Piperazin-1-ylphenyl)furo[3,2-b]pyridin-3-yl]pyridin-2-amine |
| Canonical SMILES | Nc1cc(-c2coc3cc(-c4ccc(N5CCNCC5)cc4)cnc23)ccn1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.65 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q04771 | ACVR1 | Homo sapiens | Human | PF01064 PF07714 PF08515 | 7.2 | IC50 | ChEMBL |
| P37023 | ACVRL1 | Homo sapiens | Human | PF07714 PF08515 | 6.8 | IC50 | ChEMBL |
| P36894 | BMPR1A | Homo sapiens | Human | PF01064 PF07714 PF08515 | 6.3 | IC50 | ChEMBL |
| O00238 | BMPR1B | Homo sapiens | Human | PF01064 PF07714 PF08515 | 6.3 | IC50 | ChEMBL |