Molecule Details
| InChIKey | QJVIFKMCLOJOGV-TZFWCWEWSA-N |
|---|---|
| Compound Name | [(2S)-3-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-2-[[3-(4-methoxyphenyl)-1,2-oxazol-5-yl]methyl]-3-oxopropyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid |
| Canonical SMILES | COc1ccc(-c2cc(C[C@H](CP(=O)(O)[C@@H](N)CCc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(N)=O)on2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.47 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9UIQ6 | LNPEP | Homo sapiens | Human | PF11838 PF01433 PF17900 | 8.0 | IC50 | ChEMBL;BindingDB |
| Q9NZ08 | ERAP1 | Homo sapiens | Human | PF11838 PF01433 PF17900 | 7.3 | IC50 | ChEMBL;BindingDB |
| Q6P179 | ERAP2 | Homo sapiens | Human | PF11838 PF01433 PF17900 | 7.1 | IC50 | ChEMBL;BindingDB |