Molecule Details
InChIKeyQJAPFAZHNSZLJE-CWURXVSKSA-N
Canonical SMILESCC(C)C[C@H](NC(=O)[C@@H]1CC(=O)NCCCCCCOC(=O)N[C@@H](C(C)C)C(=O)N1)[C@@H](O)C[C@@H](C)C(=O)N[C@H](C(=O)NCc1ccccc1)C(C)C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.97
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB02378
Drug NameMMI-175
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan
Cross-references: BindingDB: 16271 CHEMBL362592 ChemSpider: 395809 PDB: MMI PubChem:449218 PubChem:46506044 ZINC: ZINC000028353688
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9Y5Z0 BACE2 Homo sapiens Human PF00026 8.3 Ki ChEMBL
P56817 BACE1 Homo sapiens Human PF00026 7.6 Ki ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P56817 BACE1 Beta-secretase 1 binder targets