Molecule Details
| InChIKey | QITTZHVXBHDUGY-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(5-methyl-1H-pyrazol-3-yl)-2-(phenylthio)quinazolin-4-amine |
| Canonical SMILES | Cc1cc(Nc2nc(Sc3ccccc3)nc3ccccc23)n[nH]1 |
| Clinical Status | Clinical Multi-Target |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.9 |
| Source | ChEMBL;BindingDB;TTD_MultiTarget |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O14965 | AURKA | Homo sapiens | Human | PF00069 | 7.7 | Ki | ChEMBL;BindingDB |
| O75716 | STK16 | Homo sapiens | Human | PF00069 | 7.7 | pIC50 | TTD_MultiTarget |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 6.8 | Ki | ChEMBL;BindingDB |
| Q96GD4 | AURKB | Homo sapiens | Human | PF00069 | 6.2 | Ki | ChEMBL;BindingDB |
| P12931 | SRC | Homo sapiens | Human | PF07714 PF00017 PF00018 | 6.1 | Ki | ChEMBL;BindingDB |