Molecule Details
| InChIKey | QIGBRXMKCJKVMJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | Hydroquinone |
| Canonical SMILES | Oc1ccc(O)cc1 |
| Clinical Status | Clinical Multi-Target |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.05 |
| Source | ChEMBL;BindingDB;TTD_MultiTarget |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB09526 |
|---|---|
| Drug Name | Hydroquinone |
| CAS Number | 123-31-9 |
| Groups | approved investigational |
| ATC Codes | D11AX11 |
| Description | Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination... |
Categories: Antioxidants Benzene Derivatives Biological Factors Compounds used in a research, industrial, or household setting Depigmenting Agents Dermatologicals Melanin Synthesis Inhibitor Melanin Synthesis Inhibitors Mutagens Noxae Phenols Protective Agents Radiation-Protective Agents Toxic Actions
Cross-references: BindingDB: 26190 ChEBI: 17594 CHEMBL537 ChemSpider: 764 Drugs Product Database (DPD): 4439 C00530 D00073 PDB: HQE PharmGKB: PA449924 PubChem:785 PubChem:310265227 RxCUI: 5509 Wikipedia: Hydroquinone ZINC: ZINC000005133378
Target Activities (2)
DrugBank Target Actions (6)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P02768 | ALB | Albumin | binder | carriers |
| P10253 | GAA | Lysosomal alpha-glucosidase | product of | enzymes |
| Q9Y271 | CYSLTR1 | Cysteinyl leukotriene receptor 1 | activator | targets |
| P05106 | ITGB3 | Integrin beta-3 | antagonist | targets |
| P08514 | ITGA2B | Integrin alpha-IIb | antagonist | targets |
| P14679 | TYR | Tyrosinase | inhibitor | targets |