Molecule Details
InChIKeyQIEOFCPRKAWYFQ-UHFFFAOYSA-N
Canonical SMILESCNc1nc(-c2cc(C(=O)Nc3cccc(C(C)(C)C#N)c3)ccc2C)cc(N2CCOCC2)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.94
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P04049 RAF1 Homo sapiens Human PF00130 PF07714 PF02196 9.2 IC50 ChEMBL;BindingDB
P15056 BRAF Homo sapiens Human PF00130 PF07714 PF02196 8.7 IC50 BindingDB