Molecule Details
InChIKeyQICPQLFMWYQJGX-SFHVURJKSA-N
Compound Name4-[5-[2-(1-phenyl-ethylamino)-pyrimidin-4-yl]-1-methyl-4-(3-trifluoromethylphenyl)-1H-imidazol-2-yl]-piperidine
Canonical SMILESC[C@H](Nc1nccc(-c2c(-c3cccc(C(F)(F)F)c3)nc(C3CCNCC3)n2C)n1)c1ccccc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Homologous
Avg pChEMBL9.04
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB01761
Drug Name4-[5-[2-(1-phenyl-ethylamino)-pyrimidin-4-yl]-1-methyl-4-(3-trifluoromethylphenyl)-1H-imidazol-2-yl]-piperidine
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 15240 CHEMBL305178 ChemSpider: 394736 PDB: 084 PubChem:447721 PubChem:46506130 ZINC: ZINC000021289776
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
O15264 MAPK13 Homo sapiens Human PF00069 10.0 IC50 ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 10.0 IC50 ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 10.0 IC50 ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 9.2 IC50 ChEMBL;BindingDB
P45984 MAPK9 Homo sapiens Human PF00069 6.2 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q16539 MAPK14 Mitogen-activated protein kinase 14 binder targets