Molecule Details
InChIKeyQGXBDMJGAMFCBF-BNSUEQOYSA-N
Canonical SMILESC[C@]12CC[C@@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL6.32
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB02854
Drug NameAetiocholanolone
CAS Number53-42-9
Groups experimental
ATC Codes nan
DescriptionThe 5-beta-reduced isomer of androsterone. Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including humans. It is excreted in the urine. [PubChem]

Cross-references: BindingDB: 50191348 ChEBI: 28195 CHEMBL85799 ChemSpider: 5669 C04373 PDB: AE2 PubChem:5880 PubChem:46507911 Wikipedia: Etiocholanolone ZINC: ZINC000003875364
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P37058 HSD17B3 Homo sapiens Human PF00106 6.5 IC50 ChEMBL;BindingDB
P04278 SHBG Homo sapiens Human PF00054 6.2 Kd ChEMBL;BindingDB
DrugBank Target Actions (4)
Target Gene Target Name Action Type
P01859 P01859 Immunoglobulin heavy constant gamma 2 binder targets
P9WGT1 P9WGT1 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase binder targets
Q06520 SULT2A1 Sulfotransferase 2A1 binder targets
Q8NBQ5 HSD17B11 Estradiol 17-beta-dehydrogenase 11 binder targets