Molecule Details
| InChIKey | QGOIQRQXIWSNJF-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-[({Imidazo[1,2-a]pyridin-2-yl}methyl)sulfanyl]-5-methyl-[1,2,4]triazolo[4,3-a]quinoline |
| Canonical SMILES | Cc1cc2nnc(SCc3cn4ccccc4n3)n2c2ccccc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.38 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q86V86 | PIM3 | Homo sapiens | Human | PF00069 | 7.1 | Ki | ChEMBL |
| Q9P1W9 | PIM2 | Homo sapiens | Human | PF00069 | 6.4 | Ki | ChEMBL |
| O43293 | DAPK3 | Homo sapiens | Human | PF00069 | 6.3 | Ki | ChEMBL |
| P23443 | RPS6KB1 | Homo sapiens | Human | PF00069 PF00433 | 6.3 | Ki | ChEMBL |
| P11309 | PIM1 | Homo sapiens | Human | PF00069 | 6.2 | Ki | ChEMBL |
| P68400 | CSNK2A1 | Homo sapiens | Human | PF00069 | 6.0 | Ki | ChEMBL |