Molecule Details
InChIKeyQGNOXTFZOLDODX-UHFFFAOYSA-N
Compound NamePf-00217830
Canonical SMILESO=C1CCc2ccc(OCCCCN3CCN(c4cccc5ccccc45)CC3)nc2N1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL9.12
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12998
Drug NamePF-00217830
CAS Number846032-02-8
Groups investigational
ATC Codes nan
DescriptionPF-00217830 has been used in trials studying the treatment of Schizophrenia.
Categories: Heterocyclic Compounds, Fused-Ring
Cross-references: BindingDB: 50343277 CHEMBL1774080 ChemSpider: 9872401 PubChem:11697676 PubChem:347829135 ZINC: ZINC000034962169
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P28223 HTR2A Homo sapiens Human PF00001 9.8 Ki ChEMBL;BindingDB
P14416 DRD2 Homo sapiens Human PF00001 9.1 Ki ChEMBL;BindingDB
P08908 HTR1A Homo sapiens Human PF00001 8.4 Ki ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P14416 DRD2 D(2) dopamine receptor modulator targets