InChIKey	QGJUIPDUBHWZPV-SGTAVMJGSA-N
Compound Name	Saxagliptin
Canonical SMILES	N#C[C@@H]1C[C@@H]2C[C@@H]2N1C(=O)[C@@H](N)C12CC3CC(CC(O)(C3)C1)C2
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.48
Source	ChEMBL

DrugBank ID	DB06335
Drug Name	Saxagliptin
CAS Number	361442-04-8
Groups	approved investigational
ATC Codes	A10BD21 A10BD25 A10BH03 A10BD10
Description	Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.

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Categories: Agents causing angioedema Alimentary Tract and Metabolism Amino Acids, Peptides, and Proteins Blood Glucose Lowering Agents Bridged-Ring Compounds Cycloparaffins Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Substrates Cytochrome P-450 Substrates DPP-IV Inhibitors Drugs Used in Diabetes Drugs that are Mainly Renally Excreted Enzyme Inhibitors Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Hypoglycemia-Associated Agents Incretins OAT3/SLC22A8 Substrates Oligopeptides Oral Hypoglycemics Peptides Protease Inhibitors

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Cross-references: BindingDB: 50225074 ChEBI: 71272 CHEMBL385517 ChemSpider: 9419005 Drugs Product Database (DPD): 20524 D08996 PharmGKB: PA165958362 PubChem:11243969 PubChem:99443245 RxCUI: 1546030 Wikipedia: Saxagliptin