Molecule Details
InChIKeyQEWSTOOMTBAUAG-UHFFFAOYSA-N
Compound Name1-(4-Hydroxy-2-methylphenyl)-4-oxo-7-pyridin-4-ylquinoline-3-carbohydrazide
Canonical SMILESCc1cc(O)ccc1-n1cc(C(=O)NN)c(=O)c2ccc(-c3ccncc3)cc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)17
Pfam Stratification Cross-Family
Avg pChEMBL6.49
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (17)
Target Gene Organism Category Pfam pChEMBL Type Source
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 8.0 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.3 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.8 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.8 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.5 Ki ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 6.4 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.2 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.2 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.1 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.1 Ki ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.1 Ki ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 6.1 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.0 Ki ChEMBL