Molecule Details
| InChIKey | QENBLMVKRYFDIR-GOSISDBHSA-N |
|---|---|
| Compound Name | (5R)-3-(3-methyl-1-benzofuran-5-yl)spiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2-one |
| Canonical SMILES | Cc1coc2ccc(N3C[C@@]4(CN5CCC4CC5)OC3=O)cc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.0 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| A5X5Y0 | HTR3E | Homo sapiens | Human | PF02931 PF02932 | 8.0 | IC50 | ChEMBL |
| O95264 | HTR3B | Homo sapiens | Human | PF02931 PF02932 | 8.0 | IC50 | ChEMBL |
| P46098 | HTR3A | Homo sapiens | Human | PF02931 PF02932 | 8.0 | IC50 | ChEMBL |
| Q70Z44 | HTR3D | Homo sapiens | Human | PF02931 PF02932 | 8.0 | IC50 | ChEMBL |
| Q8WXA8 | HTR3C | Homo sapiens | Human | PF02931 PF02932 | 8.0 | IC50 | ChEMBL |