InChIKey	QDLHCMPXEPAAMD-QAIWCSMKSA-N
Compound Name	Wortmannin
Canonical SMILES	COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	13
Pfam Stratification	Cross-Family
Avg pChEMBL	7.5
Source	ChEMBL;BindingDB;TTD_MultiTarget

DrugBank ID	DB08059
Drug Name	Wortmannin
CAS Number	19545-26-7
Groups	experimental
ATC Codes	nan
Description	Wortmannin is a steroid metabolite of _Penicillium funiculosum_ and _Talaromyces wortmannii_ fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).

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Categories: Androstadienes Androstanes Androstenes Anti-Infective Agents Antidepressive Agents Antifungal Agents Central Nervous System Depressants Enzyme Inhibitors Fused-Ring Compounds Hormone Antagonists Hormones, Hormone Substitutes, and Hormone Antagonists Immunologic Factors Immunosuppressive Agents Insulin Antagonists Protein Kinase Inhibitors Radiation-Sensitizing Agents Serotonin Agents Serotonin Receptor Antagonists Steroids

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Cross-references: BindingDB: 15234 ChEBI: 52289 CHEMBL428496 ChemSpider: 276037 C15181 PDB: KWT PubChem:312145 PubChem:99444530 Wikipedia: Wortmannin ZINC: ZINC000001619592