Molecule Details
InChIKeyQCLXNOBXQUWUEW-UHFFFAOYSA-N
Compound Name5-[2,3-bis(fluoranyl)phenyl]-~{N}-[[1-(2-methoxyethyl)piperidin-4-yl]methyl]-1~{H}-indazole-3-carboxamide
Canonical SMILESCOCCN1CCC(CNC(=O)c2n[nH]c3ccc(-c4cccc(F)c4F)cc23)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.0
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P49841 GSK3B Homo sapiens Human PF00069 7.7 IC50 ChEMBL;BindingDB
P49840 GSK3A Homo sapiens Human PF00069 7.4 IC50 ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.4 IC50 ChEMBL
Q12809 KCNH2 Homo sapiens Human PF00027 PF00520 PF13426 7.3 IC50 ChEMBL;BindingDB
P49759 CLK1 Homo sapiens Human PF00069 7.2 IC50 ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.8 IC50 ChEMBL
Q13164 MAPK7 Homo sapiens Human PF00069 6.7 IC50 ChEMBL;BindingDB
P25098 GRK2 Homo sapiens Human PF00169 PF00069 PF00615 6.3 IC50 ChEMBL;BindingDB
Q92630 DYRK2 Homo sapiens Human PF00069 6.3 IC50 ChEMBL;BindingDB