Molecule Details
| InChIKey | QBUWDNJZVDZAFK-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-[(3-chlorophenyl)methyl]-N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-4-methyl-1,3-thiazol-2-amine |
| Canonical SMILES | COc1cc(Nc2nc(C)c(Cc3cccc(Cl)c3)s2)ccc1-c1cnco1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 7 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.13 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (7)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P12268 | IMPDH2 | Homo sapiens | Human | PF00571 PF00478 | 6.4 | IC50 | ChEMBL;BindingDB |
| P49768 | PSEN1 | Homo sapiens | Human | PF01080 | 6.1 | IC50 | ChEMBL |
| P49810 | PSEN2 | Homo sapiens | Human | PF01080 | 6.1 | IC50 | ChEMBL |
| Q8WW43 | APH1B | Homo sapiens | Human | PF06105 | 6.1 | IC50 | ChEMBL |
| Q92542 | NCSTN | Homo sapiens | Human | PF18266 PF05450 | 6.1 | IC50 | ChEMBL |
| Q96BI3 | APH1A | Homo sapiens | Human | PF06105 | 6.1 | IC50 | ChEMBL |
| Q9NZ42 | PSENEN | Homo sapiens | Human | PF10251 | 6.1 | IC50 | ChEMBL |