Molecule Details
| InChIKey | QAOAOVKBIIKRNL-UHFFFAOYSA-N |
|---|---|
| Compound Name | MK 886 |
| Canonical SMILES | CC(C)c1ccc2c(c1)c(SC(C)(C)C)c(CC(C)(C)C(=O)O)n2Cc1ccc(Cl)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.74 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB16739 |
|---|---|
| Drug Name | MK-886 |
| CAS Number | 118414-82-7 |
| Groups | experimental |
| ATC Codes | nan |
| Description | MK-886 is an experimental inhibitor of leukotriene synthesis. |
Categories: Benzene Derivatives Enzyme Inhibitors Heterocyclic Compounds, Fused-Ring Hydrocarbons, Chlorinated Hydrocarbons, Halogenated Lipoxygenase Inhibitors PPAR alpha, antagonists & inhibitors
Cross-references: BindingDB: 50006805 ChEBI: 75390 CHEMBL29097 ChemSpider: 2885052 PDB: QY7 Wikipedia: MK-886 ZINC: ZINC000001536875