Molecule Details
InChIKeyPYQFQGXOARMGAQ-UHFFFAOYSA-N
Compound Name3-(2-aminopyrimidin-4-yl)-6-bromo-1H-indol-4-ol
Canonical SMILESNc1nccc(-c2c[nH]c3cc(Br)cc(O)c23)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL6.21
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
P17612 PRKACA Homo sapiens Human PF00069 6.7 IC50 ChEMBL
P22612 PRKACG Homo sapiens Human PF00069 6.7 IC50 ChEMBL
P22694 PRKACB Homo sapiens Human PF00069 6.7 IC50 ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.3 IC50 ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.0 IC50 ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.0 IC50 ChEMBL
P49674 CSNK1E Homo sapiens Human PF00069 6.0 IC50 ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.0 IC50 ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.0 IC50 ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 6.0 IC50 ChEMBL;BindingDB
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.0 IC50 ChEMBL