Molecule Details
InChIKeyPXRDIWAVNLQFBI-UHFFFAOYSA-N
Compound Name4-(4-Benzylphenylamino)-6-(2-morpholinoethylamino)-1,7-naphthyridine-3-carbonitrile
Canonical SMILESN#Cc1cnc2cnc(NCCN3CCOCC3)cc2c1Nc1ccc(Cc2ccccc2)cc1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)6
Pfam Stratification Homologous
Avg pChEMBL6.55
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P41279 MAP3K8 Homo sapiens Human PF00069 8.7 IC50 ChEMBL;BindingDB
Q02750 MAP2K1 Homo sapiens Human PF00069 6.2 IC50 ChEMBL;BindingDB
O15264 MAPK13 Homo sapiens Human PF00069 6.1 IC50 ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 6.1 IC50 ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 6.1 IC50 ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 6.1 IC50 ChEMBL