4-(6-fluoronaphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one

InChIKey	`PXOJJCCSYAVCPK-UHFFFAOYSA-N`
Compound Name	4-(6-fluoronaphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one
Canonical SMILES	`O=c1[nH]nc(-c2ccnc(NC3CCOCC3)c2)n1-c1ccc2cc(F)ccc2c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.67
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P53779	MAPK10	Homo sapiens	Human	PF00069	7.2	IC50	ChEMBL;BindingDB
P45984	MAPK9	Homo sapiens	Human	PF00069	6.7	IC50	ChEMBL;BindingDB
P45983	MAPK8	Homo sapiens	Human	PF00069	6.1	IC50	ChEMBL;BindingDB