Molecule Details
| InChIKey | PWRPUAKXMQAFCJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | Perlapine |
| Canonical SMILES | CN1CCN(C2=Nc3ccccc3Cc3ccccc32)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.25 |
| Source | BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB19952 |
|---|---|
| Drug Name | Perlapine |
| CAS Number | 1977-11-3 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Perlapine is a small molecule drug. Perlapine has a monoisotopic molecular weight of 291.17 Da. |
Categories: Heterocyclic Compounds, Fused-Ring
Cross-references: BindingDB: 50102325 ChEBI: 31983 CHEMBL340801 ZINC: ZINC000027303430
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 7.7 | Ki | BindingDB |
| P21917 | DRD4 | Homo sapiens | Human | PF00001 | 7.5 | Ki | BindingDB |
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 7.2 | Ki | BindingDB |
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 7.0 | Ki | BindingDB |
| P50406 | HTR6 | Homo sapiens | Human | PF00001 | 6.8 | Ki | BindingDB |