Molecule Details
| InChIKey | PWEXGFMQMFFMNN-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-[2-(2,2-difluoro-6-azaspiro[2.5]octan-6-yl)-5-ethylsulfonylphenyl]-2-methyl-7H-cyclopenta[c]pyridin-1-one |
| Canonical SMILES | CCS(=O)(=O)c1ccc(N2CCC3(CC2)CC3(F)F)c(-c2cn(C)c(=O)c3c2C=CC3)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.35 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P25440 | BRD2 | Homo sapiens | Human | PF17035 PF00439 | 8.8 | IC50 | BindingDB |
| Q15059 | BRD3 | Homo sapiens | Human | PF17035 PF00439 | 8.4 | IC50 | BindingDB |
| O60885 | BRD4 | Homo sapiens | Human | PF17035 PF17105 PF00439 | 8.4 | IC50 | BindingDB |
| Q58F21 | BRDT | Homo sapiens | Human | PF17035 PF17105 PF00439 | 7.8 | IC50 | BindingDB |