Molecule Details
| InChIKey | PVLJETXTTWAYEW-UHFFFAOYSA-N |
|---|---|
| Canonical SMILES | CN(c1nccc(=O)[nH]1)C1CCN(c2nc3ccccc3n2Cc2ccc(F)cc2)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.46 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB12523 |
|---|---|
| Drug Name | Mizolastine |
| CAS Number | 108612-45-9 |
| Groups | approved |
| ATC Codes | R06AX25 |
| Description | Mizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers). |
Categories: Antihistamines for Systemic Use Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 Enzyme Inhibitors Heterocyclic Compounds, Fused-Ring Histamine Agents Histamine Antagonists Histamine H1 Antagonists Histamine H1 Antagonists, Non-Sedating Moderate Risk QTc-Prolonging Agents Neurotransmitter Agents QTc Prolonging Agents
Cross-references: BindingDB: 22877 ChEBI: 31857 CHEMBL94454 ChemSpider: 59315 PharmGKB: PA166129535 PubChem:65906 PubChem:347828752 RxCUI: 61455 Wikipedia: Mizolastine ZINC: ZINC000013831810