Molecule Details
InChIKeyPTYZWRDJQNYYOD-UHFFFAOYSA-N
Canonical SMILESCSc1ccc(OC(F)F)c(-c2n[nH]cc2NC(=O)c2cnc3cccnn23)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL10.15
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 10.3 Ki ChEMBL
P23458 JAK1 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 10.0 Ki ChEMBL