Molecule Details
| InChIKey | PTSASYUIHCGRFT-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(1'-benzyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-hydroxyprop-2-enamide |
| Canonical SMILES | O=C(C=Cc1ccc2c(c1)C(=O)CC1(CCN(Cc3ccccc3)CC1)O2)NO |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.28 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O15379 | HDAC3 | Homo sapiens | Human | PF00850 | 7.6 | IC50 | BindingDB |
| Q9UBN7 | HDAC6 | Homo sapiens | Human | PF00850 PF02148 | 7.6 | IC50 | BindingDB |
| Q13547 | HDAC1 | Homo sapiens | Human | PF00850 | 7.0 | IC50 | BindingDB |
| P56524 | HDAC4 | Homo sapiens | Human | PF12203 PF00850 | 6.9 | IC50 | BindingDB |