Molecule Details
InChIKeyPTCBNPULJWGSML-UHFFFAOYSA-N
Compound NameGdc-0276
Canonical SMILESO=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.99
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q15858 SCN9A Homo sapiens Human PF00520 PF24609 PF06512 PF11933 9.4 IC50 ChEMBL;BindingDB
Q01118 SCN7A Homo sapiens Human PF00520 PF24609 PF06512 9.2 IC50 ChEMBL
P35499 SCN4A Homo sapiens Human PF00520 PF24609 PF06512 8.1 IC50 ChEMBL
O60939 SCN2B Homo sapiens Human PF07686 8.0 IC50 ChEMBL
P35498 SCN1A Homo sapiens Human PF00520 PF24609 PF06512 PF11933 8.0 IC50 ChEMBL
Q07699 SCN1B Homo sapiens Human PF07686 8.0 IC50 ChEMBL
Q99250 SCN2A Homo sapiens Human PF00520 PF24609 PF06512 PF11933 7.7 IC50 ChEMBL
Q14524 SCN5A Homo sapiens Human PF00520 PF24609 PF06512 PF11933 7.3 IC50 ChEMBL
Q9UQD0 SCN8A Homo sapiens Human PF00520 PF24609 PF06512 PF11933 6.3 IC50 ChEMBL