[4-[[7-Cyclopentyl-6-(1,3-oxazol-5-yl)pyrrolo[2,3-d]pyrimidin-2-yl]amino]-1-methylpyrrol-2-yl]-(4-methylpiperazin-1-yl)methanone

InChIKey	`PSWIPMICOQJHRP-UHFFFAOYSA-N`
Compound Name	[4-[[7-Cyclopentyl-6-(1,3-oxazol-5-yl)pyrrolo[2,3-d]pyrimidin-2-yl]amino]-1-methylpyrrol-2-yl]-(4-methylpiperazin-1-yl)methanone
Canonical SMILES	`CN1CCN(C(=O)c2cc(Nc3ncc4cc(-c5cnco5)n(C5CCCC5)c4n3)cn2C)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.22
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O14965	AURKA	Homo sapiens	Human	PF00069	8.7	IC50	ChEMBL;BindingDB
Q96GD4	AURKB	Homo sapiens	Human	PF00069	8.4	IC50	ChEMBL;BindingDB
P06493	CDK1	Homo sapiens	Human	PF00069	7.5	IC50	ChEMBL;BindingDB