Molecule Details
InChIKeyPSTHAQGLUUIJDB-CHSHITCJSA-N
Compound NameC-Met inhibitors
Canonical SMILESCOc1cc2c(Oc3ccc(NC(=O)N/N=C/c4ccc(F)cc4F)cc3F)ccnc2cc1OCCCN1CCC(C)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Homologous
Avg pChEMBL7.03
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 8.8 IC50 ChEMBL
Q04912 MST1R Homo sapiens Human PF07714 PF01437 PF01403 PF01833 7.7 IC50 ChEMBL
P10721 KIT Homo sapiens Human PF00047 PF07714 6.6 IC50 ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.4 IC50 ChEMBL
P16234 PDGFRA Homo sapiens Human PF07679 PF25305 PF07714 6.4 IC50 ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.2 IC50 ChEMBL