Molecule Details
| InChIKey | PSNGTIQWNUJCAN-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-Amino-5,5-diphenyl-3-(2-phenylbutyl)imidazol-4-one |
| Canonical SMILES | CCC(CN1C(=N)NC(c2ccccc2)(c2ccccc2)C1=O)c1ccccc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.01 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P14091 | CTSE | Homo sapiens | Human | PF07966 PF00026 | 7.0 | IC50 | ChEMBL;BindingDB |
| P07339 | CTSD | Homo sapiens | Human | PF07966 PF00026 | 6.4 | IC50 | ChEMBL;BindingDB |
| P46925 | PMII | Plasmodium falciparum (isolate HB3) | Pathogen | PF00026 | 7.9 | IC50 | ChEMBL;BindingDB |
| Q17SB2 | Plasmodium falciparum | Pathogen | PF00026 | 7.3 | IC50 | ChEMBL | |
| Q8IM16 | PMIV | Plasmodium falciparum (isolate 3D7) | Pathogen | PF00026 | 7.3 | IC50 | BindingDB |
| Q8I6Z5 | PMV | Plasmodium falciparum (isolate 3D7) | Pathogen | PF00026 PF14543 | 6.0 | IC50 | ChEMBL |