Molecule Details
InChIKeyPRRYQINUAIQTFJ-UHFFFAOYSA-N
Compound Name5-Phenyl4-piperidin-1-yl-7H-pyrrolo[2,3-d]pyrimidine
Canonical SMILESc1ccc(-c2c[nH]c3ncnc(N4CCCCC4)c23)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL6.7
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 7.7 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 7.5 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 7.2 Ki ChEMBL
Q96L34 MARK4 Homo sapiens Human PF02149 PF00069 PF00627 7.1 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.9 Ki ChEMBL
Q02750 MAP2K1 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.3 Ki ChEMBL
Q9H0K1 SIK2 Homo sapiens Human PF00069 PF23312 6.3 Ki ChEMBL
Q02779 MAP3K10 Homo sapiens Human PF07714 PF14604 6.2 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.0 Ki ChEMBL
P10721 KIT Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL