Molecule Details
InChIKeyPRDPUQGHWRZOIL-QCDSWUKFSA-N
Compound Name(2'S,3R)-2'-[3-[4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl]-1H-indazol-6-yl]-5-methoxyspiro[1H-indole-3,1'-cyclopropane]-2-one
Canonical SMILESCOc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(-c4ccc(N5CCN(CCO)CC5)cc4)n[nH]c3c1)C(=O)N2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL8.06
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 8.9 IC50 ChEMBL;BindingDB
Q96GD4 AURKB Homo sapiens Human PF00069 8.2 IC50 ChEMBL;BindingDB
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.1 IC50 ChEMBL;BindingDB