Molecule Details
InChIKeyPQGDUNWRHHLMNT-UHFFFAOYSA-N
Compound NameGABAA receptor agent 5
Canonical SMILESO=C(Nc1cccc(C(=O)N2CCC3(CCNCC3)CC2)c1)c1cccs1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Homologous
Avg pChEMBL6.82
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P31644 GABRA5 Homo sapiens Human PF02931 PF02932 7.3 IC50 ChEMBL;BindingDB
P34903 GABRA3 Homo sapiens Human PF02931 PF02932 7.1 IC50 ChEMBL;BindingDB
P18505 GABRB1 Homo sapiens Human PF02931 PF02932 7.1 Ki ChEMBL
P48169 GABRA4 Homo sapiens Human PF02931 PF02932 7.1 Ki ChEMBL;BindingDB
O14764 GABRD Homo sapiens Human PF02931 PF02932 6.8 IC50 ChEMBL
P18507 GABRG2 Homo sapiens Human PF02931 PF02932 6.8 IC50 ChEMBL
P47870 GABRB2 Homo sapiens Human PF02931 PF02932 6.6 IC50 ChEMBL
P47869 GABRA2 Homo sapiens Human PF02931 PF02932 6.5 IC50 ChEMBL;BindingDB
P14867 GABRA1 Homo sapiens Human PF02931 PF02932 6.1 IC50 ChEMBL;BindingDB