Molecule Details
| InChIKey | PQEIMHBVHXTVNA-UHFFFAOYSA-N |
|---|---|
| Compound Name | mTOR inhibitor-2 |
| Canonical SMILES | N#CCN1CCC(n2c(=O)cnc3cnc4ccc(-c5ccc(N)nc5)cc4c32)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.82 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P42345 | MTOR | Homo sapiens | Human | PF02259 PF02260 PF08771 PF23593 PF11865 PF00454 | 8.1 | IC50 | ChEMBL;BindingDB |
| P62942 | FKBP1A | Homo sapiens | Human | PF00254 | 8.1 | IC50 | ChEMBL |
| P68106 | FKBP1B | Homo sapiens | Human | PF00254 | 8.1 | IC50 | ChEMBL |
| P78527 | PRKDC | Homo sapiens | Human | PF20500 PF20502 PF08163 PF19704 PF02259 PF02260 PF00454 | 7.6 | IC50 | ChEMBL;BindingDB |
| Q13315 | ATM | Homo sapiens | Human | PF02259 PF02260 PF00454 PF11640 | 7.2 | IC50 | ChEMBL;BindingDB |