Molecule Details
| InChIKey | PPQSZAVBAJMLRF-WJDWOHSUSA-N |
|---|---|
| Compound Name | (5Z)-2-cycloheptylimino-5-[(1-methylindazol-5-yl)methylidene]imidazolidin-4-one |
| Canonical SMILES | Cn1ncc2cc(/C=C3\N=C(NC4CCCCCC4)NC3=O)ccc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.55 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q13627 | DYRK1A | Homo sapiens | Human | PF00069 | 7.4 | IC50 | ChEMBL |
| P49761 | CLK3 | Homo sapiens | Human | PF00069 | 6.4 | IC50 | ChEMBL |
| Q9Y463 | DYRK1B | Homo sapiens | Human | PF00069 | 6.4 | IC50 | ChEMBL |
| Q9HAZ1 | CLK4 | Homo sapiens | Human | PF00069 | 6.4 | IC50 | ChEMBL |
| O43781 | DYRK3 | Homo sapiens | Human | PF00069 | 6.2 | IC50 | ChEMBL |