Molecule Details
| InChIKey | PPMGWZOVBXDTHU-UHFFFAOYSA-N |
|---|---|
| Compound Name | 7-(4-chlorophenyl)-N'-hydroxy-2-methylpyrazolo[1,5-a]pyrimidine-3-carboximidamide |
| Canonical SMILES | Cc1nn2c(-c3ccc(Cl)cc3)ccnc2c1/C(N)=N/O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.56 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P04629 | NTRK1 | Homo sapiens | Human | PF13855 PF16920 PF07714 PF18613 | 6.7 | IC50 | ChEMBL |
| P68400 | CSNK2A1 | Homo sapiens | Human | PF00069 | 6.7 | IC50 | ChEMBL |
| O14757 | CHEK1 | Homo sapiens | Human | PF00069 | 6.5 | IC50 | ChEMBL |
| P11309 | PIM1 | Homo sapiens | Human | PF00069 | 6.4 | IC50 | ChEMBL |