InChIKey	POZRVZJJTULAOH-LHZXLZLDSA-N
Compound Name	Danazol
Canonical SMILES	C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=Cc5oncc5C[C@]4(C)[C@H]3CC[C@@]21C
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.48
Source	ChEMBL;BindingDB

DrugBank ID	DB01406
Drug Name	Danazol
CAS Number	17230-88-5
Groups	approved investigational
ATC Codes	G03XA01
Description	A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorde...

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Categories: Androgens Antigonadotropins and Similar Agents Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (moderate) Cytochrome P-450 CYP3A4 Inhibitors (strong) Cytochrome P-450 Enzyme Inhibitors Estrogen Antagonists Fused-Ring Compounds Genito Urinary System and Sex Hormones Hormone Antagonists Hormones, Hormone Substitutes, and Hormone Antagonists Hyperglycemia-Associated Agents Pregnadienes Pregnanes Sex Hormones and Modulators of the Genital System Steroids Thyroxine-binding globulin inhibitors

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Cross-references: BindingDB: 50423541 ChEBI: 4315 CHEMBL1479 ChemSpider: 26436 Drugs Product Database (DPD): 2282 D00289 PDB: QA1 PharmGKB: PA164749056 PubChem:28417 PubChem:46506475 RxCUI: 3102 Therapeutic Targets Database: DAP001017 Wikipedia: Danazol ZINC: ZINC000003881958