Molecule Details
| InChIKey | POKUGRIXYDIRKM-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-[2-(Cyclopropylsulfonylmethyl)-6-(2,4-difluorophenyl)-4-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine |
| Canonical SMILES | Cn1cc(-c2ccn3c(-c4cc(CS(=O)(=O)C5CC5)nc(-c5ccc(F)cc5F)c4)cnc3c2)cn1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.43 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P21802 | FGFR2 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 8.5 | IC50 | BindingDB |
| P35968 | KDR | Homo sapiens | Human | PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 | 8.4 | IC50 | BindingDB |
| P11362 | FGFR1 | Homo sapiens | Human | PF07679 PF00047 PF07714 | 8.3 | IC50 | BindingDB |