Molecule Details
InChIKeyPNRKMBJQIFDKIH-BXKNEMSHSA-N
Canonical SMILESCOc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1cnc(N(C)C[C@H]3CC[C@H](N4CCN(C)C(=O)C4)CC3)cn1)C(=O)C2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL8.24
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q00987 MDM2 Homo sapiens Human PF02201 PF13920 PF00641 8.4 IC50 ChEMBL;BindingDB
P04637 TP53 Homo sapiens Human PF00870 PF08563 PF07710 PF18521 8.1 IC50 ChEMBL