10-(2-methyl-4-pyridinyl)-N-[3-(trifluoromethyl)phenyl]-5,6-dihydro-[1,2,4]triazolo[4,3-d][1,4]benzoxazepin-3-amine

InChIKey	`PNOVIOUSABCJCS-UHFFFAOYSA-N`
Compound Name	10-(2-methyl-4-pyridinyl)-N-[3-(trifluoromethyl)phenyl]-5,6-dihydro-[1,2,4]triazolo[4,3-d][1,4]benzoxazepin-3-amine
Canonical SMILES	`Cc1cc(-c2ccc3c(c2)-c2nnc(Nc4cccc(C(F)(F)F)c4)n2CCO3)ccn1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.7
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q7Z601	GPR142	Homo sapiens	Human	PF00001	7.2	IC50	ChEMBL;BindingDB
P10635	CYP2D6	Homo sapiens	Human	PF00067	6.5	IC50	ChEMBL;BindingDB
Q12809	KCNH2	Homo sapiens	Human	PF00027 PF00520 PF13426	6.4	IC50	ChEMBL;BindingDB