Molecule Details
| InChIKey | PMWPKMYJPGCYEL-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-[4-Chloro-3-(difluoromethoxy)phenyl]-4-(imidazol-1-ylmethyl)triazole |
| Canonical SMILES | FC(F)Oc1cc(-n2cc(Cn3ccnc3)nn2)ccc1Cl |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.06 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P10635 | CYP2D6 | Homo sapiens | Human | PF00067 | 7.5 | IC50 | ChEMBL |
| Q05586 | GRIN1 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.2 | IC50 | ChEMBL |
| Q13224 | GRIN2B | Homo sapiens | Human | PF01094 PF00060 PF10613 PF10565 | 7.2 | IC50 | ChEMBL |
| P05177 | CYP1A2 | Homo sapiens | Human | PF00067 | 7.0 | IC50 | ChEMBL |
| P33261 | CYP2C19 | Homo sapiens | Human | PF00067 | 6.4 | IC50 | ChEMBL |