2-[[1-[3-(1,1-difluoroethyl)-4-fluorophenyl]triazol-4-yl]methoxy]-5-(1H-pyrazol-4-yl)pyrimidine

InChIKey	`PMKZADUSIHBBGK-UHFFFAOYSA-N`
Compound Name	2-[[1-[3-(1,1-difluoroethyl)-4-fluorophenyl]triazol-4-yl]methoxy]-5-(1H-pyrazol-4-yl)pyrimidine
Canonical SMILES	`CC(F)(F)c1cc(-n2cc(COc3ncc(-c4cn[nH]c4)cn3)nn2)ccc1F`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.78
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P19793	RXRA	Homo sapiens	Human	PF00104 PF11825 PF00105	6.8	IC50	ChEMBL;BindingDB
Q05586	GRIN1	Homo sapiens	Human	PF01094 PF00060 PF10613	6.8	IC50	ChEMBL;BindingDB
Q13224	GRIN2B	Homo sapiens	Human	PF01094 PF00060 PF10613 PF10565	6.8	IC50	ChEMBL