Molecule Details
InChIKeyPLWROONZUDKYKG-DOFZRALJSA-N
Compound Name(6Z,9Z,12Z,15Z)-1,1,1-Trifluoro-6,9,12,15-heneicosatetraen-2-one
Canonical SMILESCCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)C(F)(F)F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL6.8
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB17022
Drug NameArachidonyltrifluoromethane
CAS Number149301-79-1
Groups experimental
ATC Codes nan
DescriptionSpecific inhibitor of phospholipase A2.[A252972]
Categories: Eicosanoids Enzyme Inhibitors Fatty Acids Fatty Acids, Essential Fatty Acids, Unsaturated Lipids
Cross-references: BindingDB: 50059523 ChEBI: 2341 CHEMBL281211 ChemSpider: 4444095 C01397 ZINC: ZINC000003813524
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
O00519 FAAH Homo sapiens Human PF01425 7.9 IC50 ChEMBL;BindingDB
Q9UP65 PLA2G4C Homo sapiens Human PF01735 6.4 IC50 ChEMBL;BindingDB
P0C869 PLA2G4B Homo sapiens Human PF00168 PF18695 PF01735 6.1 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P47712 PLA2G4A Cytosolic phospholipase A2 inhibitor targets