Molecule Details
InChIKeyPJTGSIKANITYOO-RCOXNQKVSA-N
Canonical SMILESCC(C)N(C)[C@@H]1CC[C@H](N2CC[C@H](Nc3ncnc4ccc(C(F)(F)F)cc34)C2=O)[C@H](NS(C)(=O)=O)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.97
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB19004
Drug NameBMS-741672
CAS Number1386991-77-0
Groups investigational
ATC Codes nan
DescriptionBMS-741672 is under investigation in clinical trial NCT00699790 (Proof of Confidence Study of CCR2 Antagonist (BMS-741672) in Insulin Resistance).

Cross-references: BindingDB: 50509862 CHEMBL4457723 ChemSpider: 129186570
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P41597 CCR2 Homo sapiens Human PF00001 9.4 IC50 ChEMBL;BindingDB
P51681 CCR5 Homo sapiens Human PF00001 6.5 IC50 ChEMBL;BindingDB