4-[[5-Fluoro-4-(8-fluoro-4-propan-2-yl-2,3-dihydro-1,4-benzoxazin-6-yl)pyrimidin-2-yl]amino]-1-(1,2,3,6-tetrahydropyridin-4-yl)pyridin-2-one

InChIKey	`PJJRCQULLSOBAU-UHFFFAOYSA-N`
Compound Name	4-[[5-Fluoro-4-(8-fluoro-4-propan-2-yl-2,3-dihydro-1,4-benzoxazin-6-yl)pyrimidin-2-yl]amino]-1-(1,2,3,6-tetrahydropyridin-4-yl)pyridin-2-one
Canonical SMILES	`CC(C)N1CCOc2c(F)cc(-c3nc(Nc4ccn(C5=CCNCC5)c(=O)c4)ncc3F)cc21`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.0
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P11802	CDK4	Homo sapiens	Human	PF00069	8.4	IC50	ChEMBL;BindingDB
Q00534	CDK6	Homo sapiens	Human	PF00069	8.1	IC50	ChEMBL;BindingDB
P07333	CSF1R	Homo sapiens	Human	PF00047 PF25305 PF07714	7.5	IC50	ChEMBL;BindingDB