N-tert-Butyl-2-{(3R,5R)-8-chloro-3-[3-(3-chloro-phenyl)-ureido]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetamide

InChIKey	`PIYVAPZSWIDNTQ-DNQXCXABSA-N`
Compound Name	N-tert-Butyl-2-{(3R,5R)-8-chloro-3-[3-(3-chloro-phenyl)-ureido]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetamide
Canonical SMILES	`CC(C)(C)NC(=O)CN1C(=O)[C@H](NC(=O)Nc2cccc(Cl)c2)C[C@H](c2ccccc2)c2ccc(Cl)cc21`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.17
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P32238	CCKAR	Homo sapiens	Human	PF00001 PF09193	8.2	pIC50	TTD_MultiTarget
P32239	CCKBR	Homo sapiens	Human	PF00001	8.2	IC50	ChEMBL;BindingDB