2-[3-[5-Methyl-2-[(3-methyl-1,2-thiazol-5-yl)amino]pyrimidin-4-yl]-3,9-diazabicyclo[3.3.1]nonan-9-yl]acetonitrile

InChIKey	`PIAOPVOJTUSVEB-UHFFFAOYSA-N`
Compound Name	2-[3-[5-Methyl-2-[(3-methyl-1,2-thiazol-5-yl)amino]pyrimidin-4-yl]-3,9-diazabicyclo[3.3.1]nonan-9-yl]acetonitrile
Canonical SMILES	`Cc1cc(Nc2ncc(C)c(N3CC4CCCC(C3)N4CC#N)n2)sn1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.94
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O60674	JAK2	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	8.3	IC50	ChEMBL
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.4	IC50	ChEMBL
P40763	STAT3	Homo sapiens	Human	PF00017 PF01017 PF02864 PF02865 PF21354	6.1	IC50	ChEMBL