Molecule Details
InChIKeyPHWHNHYZZNJPLB-QMMMGPOBSA-N
Compound NameSdccggsk-0000248.P001
Canonical SMILESCCn1c(-c2nonc2N)nc2cncc(C(=O)N3CC[C@H](N)C3)c21
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)6
Pfam Stratification Homologous
Avg pChEMBL7.45
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 8.2 IC50 ChEMBL;BindingDB
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 8.2 IC50 ChEMBL;BindingDB
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 7.8 IC50 ChEMBL;BindingDB
Q15418 RPS6KA1 Homo sapiens Human PF00069 PF00433 7.5 IC50 ChEMBL;BindingDB
P24941 CDK2 Homo sapiens Human PF00069 6.5 pIC50 TTD_MultiTarget
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 6.5 pIC50 TTD_MultiTarget