InChIKey	PHWBOXQYWZNQIN-UHFFFAOYSA-N
Compound Name	Ticlopidine
Canonical SMILES	Clc1ccccc1CN1CCc2sccc2C1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	6
Pfam Stratification	Cross-Family
Avg pChEMBL	6.51
Source	ChEMBL;BindingDB

DrugBank ID	DB00208
Drug Name	Ticlopidine
CAS Number	55142-85-3
Groups	approved
ATC Codes	B01AC05
Description	Ticlopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated...

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Categories: Antiplatelet agents Blood and Blood Forming Organs Cardiovascular Agents Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) Cytochrome P-450 CYP2B6 Inhibitors Cytochrome P-450 CYP2B6 Inhibitors (moderate) Cytochrome P-450 CYP2B6 Inhibitors (strong) Cytochrome P-450 CYP2C19 Inhibitors Cytochrome P-450 CYP2C19 Inhibitors (moderate) Cytochrome P-450 CYP2C19 Inhibitors (strong) Cytochrome P-450 CYP2C19 Substrates Cytochrome P-450 CYP2C8 Inhibitors Cytochrome P-450 CYP2C8 Inhibitors (weak) Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors (weak) Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP2E1 Inhibitors Cytochrome P-450 CYP2E1 Inhibitors (weak) Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Decreased Platelet Aggregation Drugs that are Mainly Renally Excreted Enzyme Inhibitors Fibrin Modulating Agents Hematologic Agents Heterocyclic Compounds, Fused-Ring Neurotransmitter Agents Platelet Aggregation Inhibitors Excl. Heparin Purinergic Agents Purinergic Antagonists Purinergic P2 Receptor Antagonists Purinergic P2Y Receptor Antagonists Pyridines Sulfur Compounds Thienopyridines Thiophenes

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Cross-references: BindingDB: 85509 ChEBI: 9588 CHEMBL833 ChemSpider: 5273 Drugs Product Database (DPD): 945 C07140 D08594 PDB: TIC PharmGKB: PA451686 PubChem:5472 PubChem:46504438 RxCUI: 10594 Therapeutic Targets Database: DAP000723 Wikipedia: Ticlopidine ZINC: ZINC000019594599