2-N-[2-[4-(6-carbamoylthieno[3,2-d]pyrimidin-4-yl)piperazin-1-yl]ethyl]-5-N-ethylthiophene-2,5-dicarboxamide

InChIKey	`PHJKODPPONELIT-UHFFFAOYSA-N`
Compound Name	2-N-[2-[4-(6-carbamoylthieno[3,2-d]pyrimidin-4-yl)piperazin-1-yl]ethyl]-5-N-ethylthiophene-2,5-dicarboxamide
Canonical SMILES	`CCNC(=O)c1ccc(C(=O)NCCN2CCN(c3ncnc4cc(C(N)=O)sc34)CC2)s1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.82
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q8IXJ6	SIRT2	Homo sapiens	Human	PF02146	8.3	IC50	ChEMBL;BindingDB
Q9NTG7	SIRT3	Homo sapiens	Human	PF02146	7.6	IC50	ChEMBL;BindingDB
Q96EB6	SIRT1	Homo sapiens	Human	PF02146	7.5	IC50	ChEMBL;BindingDB